"NASA’s Commercial Crew Program uses a loss-of-crew threshold of 0.5% for a 210-day ISS mission and 0.2% for ascent and entry."
NASA's March 2026 Inspector General report documents Commercial Crew safety thresholds of 1 in 200 for a 210-day ISS mission and 1 in 500 for ascent and entry. These design requirements demonstrate how astronaut-safety objectives are expressed as measurable probabilistic targets.
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